LABS: X-Ray Crystallography
Saturday, July 20th • 10:30 a.m. – 1:00 p.m.
540 South Marengo Avenue, Pasadena, California 91101
Grade Level: 7-12
Cost: $60 (Staff will invoice for payment after registration.)
Did you know that under the right conditions, protein and nucleic acid molecules in your body can form crystals? What could we possibly learn about their function from this crystalline state?
Over the past century, structural biologists have used a technique known as -ray crystallography to study the three-dimensional structure of molecules. When crystalline material is exposed to X-ray radiation, the electron cloud surrounding the atoms of that molecule scatter the X-ray waves in a regular array to produce a diffraction pattern. From this pattern, scientist are able to determine the shape and analyze details critical to the function of that molecule at atomic level resolution.
In this workshop, we will learn the necessary tools to solve a three-dimensional protein structure, such as crystal growth, cryo-cooling, and computational modeling into experimentally determined electron density.
Please note upon registration, a LABS Series team member will be in touch with you via email to confirm and finalize your child’s enrollment in the workshop.
About the Speaker
|Dr. Christopher Barnes has been a research scientist in the fields of chemistry, biophysics, pharmacology, immunology, and virology over the past 12 years. He holds a PhD in Molecular Pharmacology from the University of Pittsburgh, as well as a master’s degree in Chemistry from the University of North Carolina. Currently, Dr. Barnes is a HHMI Hanna Gray Postdoctoral Fellow in the laboratory of Dr. Pamela Bjorkman at Caltech, where he researches the cross-talk between HIV and our immune system in order to guide the development of an effective vaccine.|